S10: Sex Differences in CNS Injury

Chair: Katherine Helmick, MS

S10.01 - Gender and the Effects of Polytrauma: A Retrospective Cohort Comparative Analysis of Quantitative and Qualitative Assessments

   Odette Harris, MD - Stanford University

S10.02 - Sex Differences in Pediatric Brain Damage

   Jaylyn Waddell, PhD - University of Maryland

S10.03 - The Role of Estrogen in Recovery from Spinal Cord Injury: Lessons from Rodent and Porcine Models

   Candace Floyd, PhD - University of Alabama at Birmingham

The goal of this session is to highlight recent discoveries related to sex differences in CNS trauma across the research spectrum including both clinical and preclinical research. The session will include discussion of sex differences in outcomes in a Veteran population with polytrauma. Next, there will be discussion of sex differences in a preclinical model of pediatric brain damage. Lastly, there will be a discussion of the role of estrogen and estrus in rodent and large animal models of spinal cord injury.

Learning objectives:
1) Discuss the importance of sex as a biological variable in study of CNS injury
2) Understand the many ways that sex affects outcome following CNS injury
3) Describe similarities, differences, and common themes to evaluation of sex as a biological variable in clinical and preclinical studies of CNS injury